Slc6a18 - solute carrier family 6 (neurotransmitter transporter), member 18 Gene

Also Known as Xt2; B0AT3; Xtrp2; D630001K16Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 22598

Summary

Enables neutral amino acid transmembrane transporter activity. Acts upstream of or within amino acid transmembrane transport. Located in apical plasma membrane and brush border membrane. Is expressed in several structures, including metanephros. Orthologous to human SLC6A18 (solute carrier family 6 member 18). [provided by Alliance of Genome Resources, Apr 2022]

Slc6a18 Products (6)

mRNA Protein Name
NM_001040692.3 NP_001035782.1 sodium-dependent neutral amino acid transporter B(0)AT3 isoform 1
NM_001136087.2 NP_001129559.1 sodium-dependent neutral amino acid transporter B(0)AT3 isoform 2
NM_001168643.1 NP_001162114.1 sodium-dependent neutral amino acid transporter B(0)AT3 isoform 3
NM_001168644.1 NP_001162115.1 sodium-dependent neutral amino acid transporter B(0)AT3 isoform 4
NM_001168645.1 NP_001162116.1 sodium-dependent neutral amino acid transporter B(0)AT3 isoform 5
NM_001168646.1 NP_001162117.1 sodium-dependent neutral amino acid transporter B(0)AT3 isoform 6

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables neutral L-amino acid transmembrane transporter activity IMP
IMP: Inferred from mutant phenotype
26240152 MGI
enables neutral L-amino acid:sodium:chloride symporter activity IDA
IDA: Inferred from direct assay
19478081 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
17167413 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within amino acid transmembrane transport IDA
IDA: Inferred from direct assay
17167413 MGI
involved in neutral amino acid transport IDA
IDA: Inferred from direct assay
19478081 MGI
involved in renal amino acid absorption IMP
IMP: Inferred from mutant phenotype
19478081 MGI
Cellular Component GO Annotation Evidence References Source
located in apical plasma membrane IDA
IDA: Inferred from direct assay
19478081 MGI
located in brush border membrane IDA
IDA: Inferred from direct assay
17167413 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
9932288 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sodium-dependent neutral amino acid transporter B(0)AT3

  • X transporter protein 2

  • b(0)AT3

  • sodium and chloride dependent transporter Xtrp2

  • sodium- and chloride-dependent transporter XTRP2

  • solute carrier family 6 member 18

  • system B 0 neutral amino acid transporter AT3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13304 SLC6A18 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc6a18 NCBI NCBI:348932