2. Gene
  3. Lrsam1 - leucine rich repeat and sterile alpha motif containing 1 Gene

Lrsam1 - leucine rich repeat and sterile alpha motif containing 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus
Gene ID: 227738 | Gene type: protein coding

About Lrsam1

Summary

Predicted to enable ubiquitin protein Ligase activity. Predicted to be involved in several processes, including positive regulation of macroautophagy; protein ubiquitination; and ubiquitin-dependent endocytosis. Predicted to act upstream of or within Autophagy and protein transport. Predicted to be located in cytosol and membrane. Is expressed in cranial ganglion; dorsal root ganglion; hindbrain; and olfactory epithelium. Used to study Charcot-Marie-Tooth disease axonal type 2P. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease axonal type 2P. Orthologous to human LRSAM1 (leucine rich repeat and sterile alpha motif containing 1). [provided by Alliance of Genome Resources, Apr 2022]

Lrsam1 Products(19)

mRNA Protein Name
NM_001379439.1 NP_001366368.1 E3 ubiquitin-protein ligase LRSAM1 isoform a
NM_001379440.1 NP_001366369.1 E3 ubiquitin-protein ligase LRSAM1 isoform a
NM_001379441.1 NP_001366370.1 E3 ubiquitin-protein ligase LRSAM1 isoform b
NM_001379442.1 NP_001366371.1 E3 ubiquitin-protein ligase LRSAM1 isoform c
NM_001379443.1 NP_001366372.1 E3 ubiquitin-protein ligase LRSAM1 isoform d
NM_001409996.1 NP_001396925.1 E3 ubiquitin-protein ligase LRSAM1 isoform e
NM_001409997.1 NP_001396926.1 E3 ubiquitin-protein ligase LRSAM1 isoform e
NM_001409998.1 NP_001396927.1 E3 ubiquitin-protein ligase LRSAM1 isoform a
NM_001409999.1 NP_001396928.1 E3 ubiquitin-protein ligase LRSAM1 isoform a
NM_001410000.1 NP_001396929.1 E3 ubiquitin-protein ligase LRSAM1 isoform a
NM_001410001.1 NP_001396930.1 E3 ubiquitin-protein ligase LRSAM1 isoform a
NM_001410002.1 NP_001396931.1 E3 ubiquitin-protein ligase LRSAM1 isoform a
NM_001410003.1 NP_001396932.1 E3 ubiquitin-protein ligase LRSAM1 isoform f
NM_001410004.1 NP_001396933.1 E3 ubiquitin-protein ligase LRSAM1 isoform c
NM_001410005.1 NP_001396934.1 E3 ubiquitin-protein ligase LRSAM1 isoform g
NM_001410006.1 NP_001396935.1 E3 ubiquitin-protein ligase LRSAM1 isoform h
NM_001410007.1 NP_001396936.1 E3 ubiquitin-protein ligase LRSAM1 isoform h
NM_001410008.1 NP_001396937.1 E3 ubiquitin-protein ligase LRSAM1 isoform h
NM_199302.3 NP_955006.1 E3 ubiquitin-protein ligase LRSAM1 isoform a
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase LRSAM1

RING-type E3 ubiquitin transferase LRSAM1

leucine-rich repeat and sterile alpha motif-containing protein 1

tsg101-associated ligase

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-W854844A (E)-JP-2-196 TFA Ligand 97.89% Unkown
HY-RS07845 LRSAM1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lrsam1 NCBI NCBI:90678