Amigo1 - adhesion molecule with Ig like domain 1 Gene

Also Known as ali2; Amigo

Species: Mus musculus

Gene Type: protein coding
Gene ID: 229715

Summary

Enables Potassium Channel regulator activity. Involved in positive regulation of potassium ion transmembrane transport. Acts upstream of or within positive regulation of synapse assembly. Located in dendrite and neuronal cell body membrane. Part of voltage-gated Potassium Channel complex. Is expressed in several structures, including branchial arch; central nervous system; genitourinary system; gut; and sensory organ. Orthologous to human AMIGO1 (adhesion molecule with Ig like domain 1). [provided by Alliance of Genome Resources, Apr 2022]

Amigo1 Products (9)

mRNA Protein Name
NM_001004293.3 NP_001004293.1 amphoterin-induced protein 1 isoform a precursor
NM_001287093.2 NP_001274022.1 amphoterin-induced protein 1 isoform b precursor
NM_001411560.1 NP_001398489.1 amphoterin-induced protein 1 isoform a precursor
NM_001411561.1 NP_001398490.1 amphoterin-induced protein 1 isoform a precursor
NM_001411562.1 NP_001398491.1 amphoterin-induced protein 1 isoform d precursor
NM_001411563.1 NP_001398492.1 amphoterin-induced protein 1 isoform d precursor
NM_001411564.1 NP_001398493.1 amphoterin-induced protein 1 isoform e precursor
NM_001411565.1 NP_001398494.1 amphoterin-induced protein 1 isoform e precursor
NM_146137.4 NP_666249.2 amphoterin-induced protein 1 isoform a precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables potassium channel regulator activity IDA
IDA: Inferred from direct assay
22056818 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
22056818 MGI
Biological Process GO Annotation Evidence References Source
involved in positive regulation of potassium ion transmembrane transport IDA
IDA: Inferred from direct assay
22056818 MGI
acts upstream of or within positive regulation of synapse assembly IDA
IDA: Inferred from direct assay
24613359 MGI
Cellular Component GO Annotation Evidence References Source
located in dendrite IDA
IDA: Inferred from direct assay
22056818 MGI
located in neuronal cell body membrane IDA
IDA: Inferred from direct assay
22056818 MGI
part of voltage-gated potassium channel complex IDA
IDA: Inferred from direct assay
22056818 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

amphoterin-induced protein 1

  • AMIGO-1

  • alivin 2

  • amphoterin induced gene and ORF (Amigo)

Amigo1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Amigo1 Q80ZD8 Kcnb1 Mus musculus Q03717
Anti Bait CoIP
22056818
Intra
Amigo1 Q80ZD8 Kcnb1 Mus musculus Q03717
IF
22056818
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00657 AMIGO1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Amigo1 NCBI NCBI:57463