Gckr - glucokinase regulatory protein Gene
Also Known as GKRP
Species: Mus musculus
Summary
Predicted to enable several functions, including carbohydrate binding activity; enzyme inhibitor activity; and fructose-6-phosphate binding activity. Involved in positive regulation of Glucokinase activity. Acts upstream of or within cellular glucose homeostasis; negative regulation of Glucokinase activity; and protein import into nucleus. Located in nucleus. Is expressed in diencephalon lateral wall mantle layer; liver left lobe; liver right lobe; midbrain mantle layer; and retina. Human ortholog(s) of this gene implicated in end stage renal disease and type 2 diabetes mellitus. Orthologous to human GCKR (Glucokinase regulator). [provided by Alliance of Genome Resources, Apr 2022]
Gckr Products (2)
| mRNA | Protein | Name |
|---|---|---|
| NM_001374741.1 | NP_001361670.1 | glucokinase regulatory protein isoform 1 |
| NM_144909.2 | NP_659158.1 | glucokinase regulatory protein isoform 2 |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
glucokinase regulatory protein |
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS05332 | GCKR Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS08083 | MAP4K5 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS08084 | Map4k5 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS19603 | Gckr Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS26099 | Gckr Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
Compound Screening Libraries
Virtual Screening
Customize Your Library
Drug Screening Service