Foxi3 - forkhead box I3 Gene

Mus musculus

Gene ID: 232077 | Gene type: protein coding

About Foxi3

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in anatomical structure morphogenesis; cell differentiation; and regulation of transcription by RNA polymerase II. Is expressed in several structures, including alimentary system; branchial arch; embryo ectoderm; integumental system; and sensory organ. Orthologous to human FOXI3 (forkhead box I3). [provided by Alliance of Genome Resources, Apr 2022]

Foxi3 Products(1)

mRNA	Protein	Name
NM_001101464.1	NP_001094934.1	forkhead box protein I3

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IDA IDA: Inferred from direct assay	30467319	MGI
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IMP IMP: Inferred from mutant phenotype	26550799	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in epidermal cell fate specification	IMP IMP: Inferred from mutant phenotype	26450968	MGI
involved in hair follicle development	IMP IMP: Inferred from mutant phenotype	26992132	MGI
involved in otic placode development	IMP IMP: Inferred from mutant phenotype	26550799	MGI
involved in parathyroid gland development	IMP IMP: Inferred from mutant phenotype	31412026	MGI
involved in pharyngeal system development	IMP IMP: Inferred from mutant phenotype	24650709	MGI
involved in thymus development	IMP IMP: Inferred from mutant phenotype	31412026	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
is active in nucleus	IDA IDA: Inferred from direct assay	30467319	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

forkhead box protein I3

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS05055	FOXI3 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Foxi3	NCBI	NCBI:344167

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