Crebl2 - cAMP responsive element binding protein-like 2 Gene

Mus musculus

Also known as B230205M03

Gene ID: 232430 | Gene type: protein coding

About Crebl2

Summary

Predicted to enable DNA binding activity and DNA-binding transcription factor activity. Involved in several processes, including positive regulation of biosynthetic process; positive regulation of glucose import; and protein stabilization. Located in nucleus. Orthologous to human CREBL2 (cAMP responsive element binding protein like 2). [provided by Alliance of Genome Resources, Apr 2022]

Crebl2 Products(1)

mRNA	Protein	Name
NM_177687.3	NP_808355.1	cAMP-responsive element-binding protein-like 2

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	21728997	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in positive regulation of D-glucose import	IMP IMP: Inferred from mutant phenotype	21728997	MGI
involved in positive regulation of DNA-templated transcription	IMP IMP: Inferred from mutant phenotype	21728997	MGI
involved in positive regulation of fat cell differentiation	IMP IMP: Inferred from mutant phenotype	21728997	MGI
involved in positive regulation of lipid biosynthetic process	IMP IMP: Inferred from mutant phenotype	21728997	MGI
involved in positive regulation of peptidyl-serine phosphorylation	IMP IMP: Inferred from mutant phenotype	21728997	MGI
involved in protein stabilization	IMP IMP: Inferred from mutant phenotype	21728997	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in nucleus	IDA IDA: Inferred from direct assay	21728997	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

cAMP-responsive element-binding protein-like 2

Crebl2 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	Crebl2	Q32M00	Creb1	Mus musculus	Q01147	Anti Bait CoIP	21728997
Intra	Crebl2	Q32M00	Creb1	Mus musculus	Q01147	Anti Tag CoIP	21728997

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03158	CREBL2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Crebl2	NCBI	NCBI:1389

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