Arih2 - ariadne RBR E3 ubiquitin protein ligase 2 Gene

Also Known as ARI2; UIP48; TRIAD1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 23807

Summary

Predicted to enable ubiquitin conjugating enzyme binding activity and ubiquitin protein Ligase activity. Acts upstream of or within ubiquitin-dependent protein catabolic process. Predicted to be located in nucleoplasm. Predicted to be part of Cul5-RING ubiquitin Ligase complex. Predicted to be active in cytoplasm. Is expressed in several structures, including adipose tissue; alimentary system; genitourinary system; hemolymphoid system; and nervous system. Orthologous to human ARIH2 (ariadne RBR E3 ubiquitin protein Ligase 2). [provided by Alliance of Genome Resources, Apr 2022]

Arih2 Products (4)

mRNA Protein Name
NM_001357283.1 NP_001344212.1 E3 ubiquitin-protein ligase ARIH2 isoform a
NM_001357285.1 NP_001344214.1 E3 ubiquitin-protein ligase ARIH2 isoform a
NM_001357286.1 NP_001344215.1 E3 ubiquitin-protein ligase ARIH2 isoform b precursor
NM_011790.5 NP_035920.1 E3 ubiquitin-protein ligase ARIH2 isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
23179078 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within ubiquitin-dependent protein catabolic process IPI
IPI: Inferred from physical interaction
10431818 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase ARIH2

  • ARI-2

  • RING-type E3 ubiquitin transferase ARIH2

  • ariadne 2

  • ariadne homolog 2

  • protein ariadne-2 homolog

  • ubcM4-interacting protein 48

Arih2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Arih2 Q9Z1K6 Nfkbib Mus musculus Q60778
Anti Bait CoIP
23179078
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00976 ARIH2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Arih2 NCBI NCBI:10425