Capn10 - calpain 10 Gene

Also Known as Capn8; mKIAA1845

Species: Mus musculus

Gene Type: protein coding
Gene ID: 23830

Summary

Predicted to enable SNARE binding activity; calcium-dependent cysteine-type endopeptidase activity; and cytoskeletal protein binding activity. Involved in several processes, including actin Cytoskeleton reorganization; positive regulation of transport; and type B pancreatic cell apoptotic process. Acts upstream of or within positive regulation of type B pancreatic cell apoptotic process. Predicted to be located in several cellular components, including cell cortex; cytosol; and mitochondrion. Predicted to be active in cytoplasm. Is expressed in dorsal root ganglion and renal calyx. Human ortholog(s) of this gene implicated in obesity; pancreatic cancer; polycystic ovary syndrome; and type 2 diabetes mellitus. Orthologous to human CAPN10 (calpain 10). [provided by Alliance of Genome Resources, Apr 2022]

Capn10 Products (1)

mRNA Protein Name
NM_011796.2 NP_035926.2 calpain-10

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in cellular response to insulin stimulus IMP
IMP: Inferred from mutant phenotype
12974673 MGI
involved in positive regulation of D-glucose import IMP
IMP: Inferred from mutant phenotype
12974673 MGI
involved in positive regulation of intracellular transport IMP
IMP: Inferred from mutant phenotype
12974673 MGI
acts upstream of or within positive regulation of type B pancreatic cell apoptotic process IMP
IMP: Inferred from mutant phenotype
15044459 MGI
involved in regulation of actin cytoskeleton organization IMP
IMP: Inferred from mutant phenotype
12974673 MGI
involved in type B pancreatic cell apoptotic process IMP
IMP: Inferred from mutant phenotype
15044459 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

calpain-10

  • CANP 10

  • calcium-activated neutral proteinase 10

  • calpain 8

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01884 CAPN10 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Capn10 NCBI NCBI:11132