1. Gene
  2. Clca1 - chloride channel accessory 1 Gene

Clca1 - chloride channel accessory 1 Gene

Mus musculus

Also known as gob5; Clca2; Clca3; gob-5

Gene ID: 23844 | Gene type: protein coding

About Clca1

Summary

Predicted to enable intracellular calcium activated Chloride Channel activity. Predicted to act upstream of or within chloride transport. Located in microvillus and secretory granule. Is integral component of membrane. Is expressed in genitourinary system; heart; rectum lumen; retina; and thymus. Human ortholog(s) of this gene implicated in asthma and chronic obstructive pulmonary disease. Orthologous to human CLCA1 (Chloride Channel accessory 1). [provided by Alliance of Genome Resources, Apr 2022]

Clca1 Products(1)

mRNA Protein Name
NM_017474.2 NP_059502.1 calcium-activated chloride channel regulator 1 precursor
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
located in membrane IDA
IDA: Inferred from direct assay
12019299 MGI
located in microvillus IDA
IDA: Inferred from direct assay
23266329 MGI
located in secretory granule IDA
IDA: Inferred from direct assay
12019299 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

calcium-activated chloride channel regulator 1

calcium-activated chloride channel family member 3

chloride channel calcium activated 1

chloride channel calcium activated 2

chloride channel calcium activated 3

mCLCA3

protein gob-5

Orthologs Information

Species Symbol Source ID
Homo sapiens Clca1 NCBI NCBI:1179