Hspa1l - heat shock protein family A (Hsp70) member 1 like Gene

Rattus norvegicus

Also known as Hsp70-3

Gene ID: 24963 | Gene type: protein coding

About Hspa1l

Summary

Predicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and misfolded protein binding activity. Predicted to be involved in several processes, including chaperone cofactor-dependent protein refolding; positive regulation of protein targeting to mitochondrion; and protein refolding. Predicted to act upstream of or within binding activity of sperm to zona pellucida. Located in mitochondrial matrix. Human ortholog(s) of this gene implicated in Kawasaki disease; major depressive disorder; schizophrenia; systemic lupus erythematosus; and uveitis. Orthologous to human HSPA1L (heat shock protein family A (HSP70) member 1 like). [provided by Alliance of Genome Resources, Apr 2022]

Hspa1l Products(1)

mRNA	Protein	Name
NM_212546.4	NP_997711.1	heat shock 70 kDa protein 1-like

Gene Ontology

Cellular Component

Cellular Component GO Annotation	Evidence	Reference	Source
located in mitochondrial matrix	IDA IDA: Inferred from direct assay	17376863	RGD
located in mitochondrion	IDA IDA: Inferred from direct assay	18385140	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

heat shock 70 kDa protein 1-like

HSP70.3	Heat shock protein 70-1l
heat shock 70 kDa protein 1L	heat shock 70 kDa protein 3
heat shock protein 1-like	heat shock protein 70

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS06426	HSPA1L Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Hspa1l	NCBI	NCBI:3305

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