Rab3a - RAB3A, member RAS oncogene family Gene

Also Known as RAB3

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25531

Summary

Enables several functions, including ATPase binding activity; GTP binding activity; and protein C-terminus binding activity. Involved in regulation of secretion by cell; regulation of synaptic vesicle priming; and synaptic vesicle cycle. Located in several cellular components, including cytosol; secretory vesicle; and terminal bouton. Part of protein-containing complex. Is anchored component of synaptic vesicle membrane. Orthologous to human RAB3A (RAB3A, member Ras oncogene family). [provided by Alliance of Genome Resources, Apr 2022]

Rab3a Products (1)

mRNA Protein Name
NM_013018.2 NP_037150.2 ras-related protein Rab-3A

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables ATPase activator activity IDA
IDA: Inferred from direct assay
11062069 RGD
enables ATPase binding IPI
IPI: Inferred from physical interaction
11062069 RGD
enables GDP-dissociation inhibitor binding IPI
IPI: Inferred from physical interaction
12426384 RGD
enables GTP binding IDA
IDA: Inferred from direct assay
8807639 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
7532276 RGD
Biological Process GO Annotation Evidence References Source
involved in regulation of dopamine secretion IDA
IDA: Inferred from direct assay
28370453 RGD
involved in regulation of synaptic vesicle exocytosis IDA
IDA: Inferred from direct assay
28057568 RGD
involved in regulation of synaptic vesicle priming IDA
IDA: Inferred from direct assay
21689256 RGD
involved in synaptic vesicle exocytosis IMP
IMP: Inferred from mutant phenotype
16141272 RGD
involved in synaptic vesicle recycling IMP
IMP: Inferred from mutant phenotype
16141272 RGD
Cellular Component GO Annotation Evidence References Source
located in axon IDA
IDA: Inferred from direct assay
16141272 RGD
part of protein-containing complex IDA
IDA: Inferred from direct assay
12426384 RGD
located in secretory granule IDA
IDA: Inferred from direct assay
17311845 RGD
located in synaptic vesicle IDA
IDA: Inferred from direct assay
8043272 RGD
is active in synaptic vesicle membrane EXP
EXP: Inferred from Experiment
17110340 RGD
is active in synaptic vesicle membrane IDA
IDA: Inferred from direct assay
17110340 RGD
located in synaptic vesicle membrane IDA
IDA: Inferred from direct assay
20926670 RGD
located in terminal bouton IDA
IDA: Inferred from direct assay
16141272 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ras-related protein Rab-3A

  • Ras-related small GTP binding protein 3A

Rab3a Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Rab3a P63012 Rph3a Rattus norvegicus P47709
Anti Bait CoIP
16763567
Intra
Rab3a P63012 Rph3a Rattus norvegicus P47709
X-Ray Diffraction
10025402
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11555 RAB3A Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rab3a NCBI NCBI:5864