Agxt2 - alanine-glyoxylate aminotransferase 2 Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 268782

Summary

Enables beta-alanine-pyruvate transaminase activity. Predicted to be involved in carboxylic acid metabolic process and positive regulation of nitric oxide biosynthetic process. Is active in mitochondrion. Is expressed in alimentary system and liver. Orthologous to human AGXT2 (alanine--glyoxylate aminotransferase 2). [provided by Alliance of Genome Resources, Apr 2022]

Agxt2 Products (3)

mRNA Protein Name
NM_001031851.1 NP_001027021.1 alanine--glyoxylate aminotransferase 2, mitochondrial isoform 3
NM_001310735.1 NP_001297664.1 alanine--glyoxylate aminotransferase 2, mitochondrial isoform 1
NM_001310736.1 NP_001297665.1 alanine--glyoxylate aminotransferase 2, mitochondrial isoform 2

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables (R)-3-amino-2-methylpropionate-pyruvate transaminase activity IDA
IDA: Inferred from direct assay
27062388 MGI
enables beta-alanine:pyruvate transaminase activity IDA
IDA: Inferred from direct assay
27062388 MGI
Cellular Component GO Annotation Evidence References Source
is active in mitochondrion IDA
IDA: Inferred from direct assay
23023372 MGI
is active in mitochondrion IMP
IMP: Inferred from mutant phenotype
23023372 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

alanine--glyoxylate aminotransferase 2, mitochondrial

  • (R)-3-amino-2-methylpropionate--pyruvate transaminase

  • AGT 2

  • D-AIBAT

  • beta-ALAAT II

  • beta-alanine-pyruvate aminotransferase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-W023323 (S)-β-Aminoisobutyric acid hydrochloride 99.90% Unkown
HY-RS00474 AGXT2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Agxt2 NCBI NCBI:64902