GPR162 - G protein-coupled receptor 162 Gene

Also Known as A-2; GRCA

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 27239

About GPR162

This gene has 7 transcripts (splice variants), 117 orthologues and 1 paralogue. Biased expression in brain (RPKM 25.8), lung (RPKM 3.5) and 6 other tissues.

Summary

This gene was identified upon genomic analysis of a gene-dense region at human chromosome 12p13. It appears to be mainly expressed in the brain; however, its function is not known. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

GPR162 Products (2)

mRNA Protein Name
NM_014449.2 NP_055264.1 probable G-protein coupled receptor 162 isoform 1
NM_019858.2 NP_062832.1 probable G-protein coupled receptor 162 isoform 2

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

GPR162 Protein Structure

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (31 - 319)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 588 a.a.
Protein Preferred Names Protein Names

probable G-protein coupled receptor 162

  • gene rich cluster, A

GPR162 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
GPR162 Q16538 UBQLN1 Homo sapiens Q9UMX0
Y2H Prey Pooling
32296183
Intra
GPR162 Q16538 UBQLN1 Homo sapiens Q9UMX0
Validated Y2H
32296183
Intra
GPR162 Q16538 UBQLN1 Homo sapiens Q9UMX0
Y2H Array
32296183
Intra
GPR162 Q16538 UBQLN2 Homo sapiens Q9UHD9
Y2H Array
32296183
Intra
GPR162 Q16538 UBQLN2 Homo sapiens Q9UHD9
Y2H Prey Pooling
32296183
Intra
GPR162 Q16538 UBQLN2 Homo sapiens Q9UHD9
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Fanconi Anemia, Complementation Group C

  • Fanconi Anemia Complementation Group C

  • FANCC

  • Facc

  • Fac

  • Fa3

  • Fanconi Pancytopenia Type 3

  • Fanconi Pancytopenia, Type 3

  • Faces Syndrome

  • Facial Features , Anorexia, Cachexia, Eye And Skin Anomalies

  • Friedman-Goodman Syndrome

  • Abnormality Of The Face
Vitreous Detachment

  • Posterior Vitreous Detachment

  • Vitreous Syneresis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05678 GPR162 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta GPR162 VGNC VGNC:99934
Canis familiaris GPR162 VGNC VGNC:41413
Mus musculus GPR162 MGD MGI:1315214
Rattus norvegicus GPR162 RGD RGD:1307437
Bos taurus GPR162 VGNC VGNC:29567
Felis catus GPR162 VGNC VGNC:62685
Others GPR162 NCBI