Gdf11 - growth differentiation factor 11 Gene

Also Known as BMP-11

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29454

Summary

Predicted to enable cytokine activity. Involved in negative regulation of neuron differentiation. Predicted to be located in nucleoplasm. Predicted to be part of protein-containing complex. Predicted to be active in extracellular space. Orthologous to human GDF11 (Growth Differentiation Factor 11). [provided by Alliance of Genome Resources, Apr 2022]

Gdf11 Products (1)

mRNA Protein Name
NM_017203.1 NP_058899.1 growth/differentiation factor 11 precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in negative regulation of neuron differentiation IMP
IMP: Inferred from mutant phenotype
15988002 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

growth/differentiation factor 11

  • GDF-11

  • bone morphogenetic protein 11

Related Agents

  • Approval
  • Pre-clinical Phase

Approval

Inhibitory Antibodies (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P99720 Luspatercept Inhibitor 98.92% Unkown
HY-P99590A Sotatercept (mIgG2a) Inhibitor 99.93% Unkown

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05351 GDF11 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18279 Gdf11 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24757 Gdf11 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gdf11 NCBI NCBI:10220