Tomm22 - translocase of outer mitochondrial membrane 22 Gene

Rattus norvegicus

Also known as TOM22; rTOM22

Gene ID: 300075 | Gene type: protein coding

About Tomm22

Summary

Enables protein transmembrane transporter activity. Involved in positive regulation of apoptotic process; protein insertion into mitochondrial membrane; and protein targeting to mitochondrion. Located in mitochondrion. Part of mitochondrial outer membrane translocase complex. Orthologous to human TOMM22 (translocase of outer mitochondrial membrane 22). [provided by Alliance of Genome Resources, Apr 2022]

Tomm22 Products(1)

mRNA	Protein	Name
NM_212514.2	NP_997679.1	mitochondrial import receptor subunit TOM22 homolog

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	11956321	RGD
enables protein transmembrane transporter activity	IMP IMP: Inferred from mutant phenotype	18687331	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in positive regulation of apoptotic process	IMP IMP: Inferred from mutant phenotype	18687331	RGD
involved in protein insertion into mitochondrial membrane	IMP IMP: Inferred from mutant phenotype	18687331	RGD
involved in protein targeting to mitochondrion	IMP IMP: Inferred from mutant phenotype	19401463	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
part of mitochondrial outer membrane translocase complex	IDA IDA: Inferred from direct assay	14985332	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

mitochondrial import receptor subunit TOM22 homolog

translocase of outer membrane 22 kDa subunit homolog

translocase of outer mitochondrial membrane 22 homolog

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14880	TOMM22 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Tomm22	NCBI	NCBI:56993

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