2. Gene
  3. Irx1 - iroquois homeobox 1 Gene

Irx1 - iroquois homeobox 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 306659 | Gene type: protein coding

About Irx1

Summary

Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell development; negative regulation of transcription by RNA polymerase II; and neuron differentiation. Predicted to act upstream of or within proximal/distal pattern formation involved in metanephric nephron development and specification of loop of Henle identity. Predicted to be active in nucleus. Orthologous to human IRX1 (iroquois homeobox 1). [provided by Alliance of Genome Resources, Apr 2022]

Irx1 Products(1)

mRNA Protein Name
NM_001107331.2 NP_001100801.1 iroquois-class homeodomain protein IRX-1
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in positive regulation of gene expression IMP
IMP: Inferred from mutant phenotype
31640472 RGD
involved in response to organic cyclic compound IDA
IDA: Inferred from direct assay
31640472 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

iroquois-class homeodomain protein IRX-1

Iroquois related homeobox 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06920 IRX1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS06922 IRX3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Irx1 NCBI NCBI:79192