2. Gene
  3. Tns3 - tensin 3 Gene

Tns3 - tensin 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as TEM6; Tens1; F830010I22Rik

Gene ID: 319939 | Gene type: protein coding

About Tns3

Summary

Acts upstream of or within cell migration; lung alveolus development; and positive regulation of cell population proliferation. Predicted to be located in cytosol and focal adhesion. Is expressed in several structures, including craniocervical region bone; foot mesenchyme; reproductive system; spleen primordium; and tail. Orthologous to human TNS3 (tensin 3). [provided by Alliance of Genome Resources, Apr 2022]

Tns3 Products(1)

mRNA Protein Name
NM_001083587.1 NP_001077056.1 tensin-3
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables guanyl-nucleotide exchange factor adaptor activity IDA
IDA: Inferred from direct assay
27505886 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
27505886 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within bone resorption IMP
IMP: Inferred from mutant phenotype
27505886 MGI
acts upstream of cell population proliferation IMP
IMP: Inferred from mutant phenotype
15733665 MGI
acts upstream of or within endothelial cell migration IMP
IMP: Inferred from mutant phenotype
15733665 MGI
acts upstream of or within lung alveolus development IMP
IMP: Inferred from mutant phenotype
15733665 MGI
acts upstream of or within negative regulation of Rho protein signal transduction IMP
IMP: Inferred from mutant phenotype
27505886 MGI
acts upstream of or within podosome assembly IMP
IMP: Inferred from mutant phenotype
27505886 MGI
acts upstream of or within positive regulation of Rac protein signal transduction IPI
IPI: Inferred from physical interaction
27505886 MGI
acts upstream of or within positive regulation of cell population proliferation IMP
IMP: Inferred from mutant phenotype
15733665 MGI
involved in positive regulation of guanyl-nucleotide exchange factor activity IDA
IDA: Inferred from direct assay
27505886 MGI
Cellular Component GO Annotation Evidence Reference Source
located in podosome IDA
IDA: Inferred from direct assay
27505886 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tensin-3

tensin-like SH2 domain containing 1

tensin-like SH2 domain-containing protein 1

tumor endothelial marker 6

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14869 TNS3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tns3 NCBI NCBI:64759