Ifnl2 - interferon lambda 2 Gene

Also Known as Il28a; IL-28A; If1ia1; EG330496

Species: Mus musculus

Gene Type: protein coding
Gene ID: 330496

Summary

Predicted to enable interleukin-28 receptor binding activity. Involved in defense response to virus and mucosal immune response. Predicted to be located in extracellular region. Predicted to be part of interleukin-28 receptor complex. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in several diseases, including COVID-19; cryoglobulinemia; dengue hemorrhagic fever; hepatitis C; and liver disease (multiple). Orthologous to several human genes including IFNL2 (interferon lambda 2) and IFNL3 (interferon lambda 3). [provided by Alliance of Genome Resources, Apr 2022]

Ifnl2 Products (1)

mRNA Protein Name
NM_001024673.2 NP_001019844.2 interferon lambda-2 precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in defense response to virus IDA
IDA: Inferred from direct assay
21518880 MGI
involved in mucosal immune response IDA
IDA: Inferred from direct assay
21518880 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

interferon lambda-2

  • IFN-lambda-2

  • IFN-lambda2

  • interferon 1ia1

  • interferon-lambda2

  • interleukin-28A

Recombinant Ifnl2 Proteins

Cat. No. Product Name Accession Purity
HY-P700203AF Animal-Free IFN-lambda 2/IL-28A Protein, Mouse (His) AAX58714.1 (D20-V193) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06592 IFNL2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174659 Human IFNL2 mRNA / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ifnl2 NCBI NCBI:282616