Scrib - scribble planar cell polarity protein Gene

Also Known as RGD1565055

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 362938

Summary

Involved in several processes, including astrocyte cell migration; protein localization to postsynapse; and regulation of postsynaptic neurotransmitter receptor internalization. Located in cell-cell junction; cytoplasm; and postsynaptic density. Is active in glutamatergic synapse. Is extrinsic component of postsynaptic density membrane. Orthologous to human SCRIB (scribble planar cell polarity protein). [provided by Alliance of Genome Resources, Apr 2022]

Scrib Products (1)

mRNA Protein Name
NM_001191879.3 NP_001178808.1 protein scribble homolog

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
17081755 RGD
Biological Process GO Annotation Evidence References Source
involved in astrocyte cell migration IMP
IMP: Inferred from mutant phenotype
17081755 RGD
involved in neurotransmitter receptor transport, endosome to postsynaptic membrane IDA
IDA: Inferred from direct assay
25310985 RGD
involved in neurotransmitter receptor transport, endosome to postsynaptic membrane IMP
IMP: Inferred from mutant phenotype
25310985 RGD
involved in regulation of postsynaptic neurotransmitter receptor internalization IDA
IDA: Inferred from direct assay
25310985 RGD
involved in regulation of postsynaptic neurotransmitter receptor internalization IMP
IMP: Inferred from mutant phenotype
25310985 RGD
involved in vesicle-mediated transport in synapse IDA
IDA: Inferred from direct assay
25310985 RGD
involved in vesicle-mediated transport in synapse IMP
IMP: Inferred from mutant phenotype
25310985 RGD
Cellular Component GO Annotation Evidence References Source
located in cell-cell junction IDA
IDA: Inferred from direct assay
17081755 RGD
is active in extrinsic component of postsynaptic density membrane IDA
IDA: Inferred from direct assay
25310985 RGD
is active in extrinsic component of postsynaptic density membrane IMP
IMP: Inferred from mutant phenotype
25310985 RGD
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
25310985 RGD
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
25310985 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein scribble homolog

  • scribbled homolog

  • scribbled planar cell polarity protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-175276 JNK-IN-24 Inhibitor / Unkown
HY-RS12562 SCRIB Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Scrib NCBI NCBI:23513