Blk - BLK proto-oncogene, Src family tyrosine kinase Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 364403

Summary

Predicted to enable non-membrane spanning protein tyrosine kinase activity and signaling receptor binding activity. Predicted to be involved in several processes, including cell surface receptor signaling pathway; negative regulation of leukocyte proliferation; and regulation of leukocyte apoptotic process. Predicted to be extrinsic component of cytoplasmic side of plasma membrane. Human ortholog(s) of this gene implicated in maturity-onset diabetes of the young type 11 and systemic lupus erythematosus. Orthologous to human Blk (Blk proto-oncogene, Src family tyrosine kinase). [provided by Alliance of Genome Resources, Apr 2022]

Blk Products (1)

mRNA Protein Name
NM_001025751.1 NP_001020922.1 tyrosine-protein kinase Blk
Protein Preferred Names Protein Names

tyrosine-protein kinase Blk

  • B lymphoid tyrosine kinase

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-157442 GLPG3312 Inhibitor 98.63% Phase 1

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-118105 RK-20448 Inhibitor 99.38% Unkown
HY-120622 BMS-243117 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Blk NCBI NCBI:640