SPEM1 - spermatid maturation 1 Gene

Also Known as C17orf83

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 374768

About SPEM1

Cytogenetic location: 17p13.1 Genomic coordinates (GRCh38): 17:7,420,324-7,421,632 (from NCBI)

This gene has 1 transcript (splice variant), 1 gene allele and 79 orthologues. Restricted expression toward testis (RPKM 24.6).

Summary

Predicted to be involved in flagellated sperm motility and sperm individualization. Predicted to act upstream of or within spermatogenesis. Predicted to be integral component of membrane. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

SPEM1 Products (1)

mRNA	Protein	Name
NM_199339.3	NP_955371.2	spermatid maturation protein 1

Protein Preferred Names	Protein Names
spermatid maturation protein 1

SPEM1 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	SPEM1	Q8N4L4	PPP1R1A	Homo sapiens	Q13522	Anti Tag CoIP	33961781
Intra	SPEM1	Q8N4L4	PPP1R1A	Homo sapiens	Q13522	Anti Tag CoIP	28514442

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases	Alias
Spermatogenic Failure 9	Male Infertility Due To Globozoospermia SPGF9 Male Infertility Due To Round-Headed Spermatozoa Globozoospermia, Complete Globozoospermia, Total Globozoospermia Globozoospermia Syndrome Round-Headed Sperm Syndrome Globozoospermia Complete Globozoospermia Total
Spermatogenic Failure	Azoospermia Spgf Spermatogenic Failure, Susceptibility To Absent Sperm Aspermatogenesis Infertility Due To Azoospermia Hypospermatogenesis Azoospermatism
Oligospermia
Primary Ciliary Dyskinesia	Immotile Cilia Syndrome Kartagener Syndrome Dextrocardia Bronchiectasis And Sinusitis Pcd Ciliary Motility Disorders Ciliary Motility Disorder Immotile Ciliary Syndrome Ciliary Dyskinesia Primary Ics Polynesian Bronchiectasis Dextrocardia-Bronchiectasis-Sinusitis Syndrome Immotile Cilia Syndrome, Kartagener Type Primary Ciliary Dyskinesia And Situs Inversus Primary Ciliary Dyskinesia, Kartagener Type Siewert Syndrome Dyskinesia, Ciliary, Primary

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13659	SPEM1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	SPEM1	RGD	RGD:1593311
Mus musculus	SPEM1	MGD	MGI:1921538
Bos taurus	SPEM1	VGNC	VGNC:35203
Felis catus	SPEM1	VGNC	VGNC:99463
Macaca mulatta	SPEM1	VGNC	VGNC:78031
Others	SPEM1	NCBI