IGFL1 - IGF like family member 1 Gene

Also Known as UNQ644; APRG644

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 374918

About IGFL1

Cytogenetic location: 19q13.32 Genomic coordinates (GRCh38): 19:46,229,742-46,231,243 (from NCBI)

This gene has 1 transcript (splice variant), 47 orthologues and 3 paralogues. Restricted expression toward esophagus (RPKM 30.9).

Summary

The protein encoded by this gene is a member of the insulin-like growth factor family of signaling molecules. The encoded protein is synthesized as a precursor protein and is proteolytically cleaved to form a secreted mature peptide. The mature peptide binds to a receptor, which in mouse was found on the cell surface of T cells. Increased expression of this gene may be linked to psoriasis. [provided by RefSeq, Aug 2016]

IGFL1 Products (1)

mRNA Protein Name
NM_198541.2 NP_940943.1 insulin growth factor-like family member 1 precursor

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
21454693 GOA
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
21454693 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

IGFL1 Protein Structure

IGFL

IGFL: Insulin growth factor-like family (27 - 89)

  • 0
  • 100
  • 110 a.a.
Protein Preferred Names Protein Names

insulin growth factor-like family member 1

IGFL1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
IGFL1 Q6UW32 IGFLR1 Homo sapiens Q9H665
Competition Binding
21454693
Intra
IGFL1 Q6UW32 IGFLR1 Homo sapiens Q9H665
SPR
21454693
Intra
IGFL1 Q6UW32 IGFLR1 Homo sapiens Q9H665
Array
21454693
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant IGFL1 Proteins

Cat. No. Product Name Accession Purity
HY-P700450 IGFL1 Protein, Human (HEK293, hFc) Q6UW32 (A25-S110) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06632 IGFL1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown