1. Recombinant Proteins
  2. Cytokines and Growth Factors
  3. IGF family
  4. IGFL1 Protein, Human (HEK293, hFc)

IGFL1 Protein, Human (HEK293, hFc)

Cat. No.: HY-P700450
Handling Instructions

IGFL1 Protein, a probable ligand for the IGFLR1 receptor, mediates cellular responses through receptor binding. As a homodimer with disulfide linkages, IGFL1's structural arrangement suggests involvement in specific signaling events. Its homodimeric nature underscores capacity for complex interactions, emphasizing potential significance in cellular communication. Further investigations into IGFL1-IGFLR1 interaction will provide valuable insights into the functional roles of this ligand-receptor pair in signaling pathways. IGFL1 Protein, Human (HEK293, hFc) is the recombinant human-derived IGFL1 protein, expressed by HEK293, with C-hFc labeled tag. The total length of IGFL1 Protein, Human (HEK293, hFc) is 86 a.a., with molecular weight of 38.7 kDa.

For research use only. We do not sell to patients.

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Description

IGFL1 Protein, a probable ligand for the IGFLR1 receptor, mediates cellular responses through receptor binding. As a homodimer with disulfide linkages, IGFL1's structural arrangement suggests involvement in specific signaling events. Its homodimeric nature underscores capacity for complex interactions, emphasizing potential significance in cellular communication. Further investigations into IGFL1-IGFLR1 interaction will provide valuable insights into the functional roles of this ligand-receptor pair in signaling pathways. IGFL1 Protein, Human (HEK293, hFc) is the recombinant human-derived IGFL1 protein, expressed by HEK293, with C-hFc labeled tag. The total length of IGFL1 Protein, Human (HEK293, hFc) is 86 a.a., with molecular weight of 38.7 kDa.

Background

The IGFL1 protein is identified as a probable ligand for the IGFLR1 cell membrane receptor, indicating its role in mediating cellular responses through receptor binding. Existing as a homodimer with disulfide linkages, IGFL1 showcases a structural arrangement that suggests its potential involvement in specific signaling events upon binding to its cognate receptor. The homodimeric nature of IGFL1 underlines its capacity for complex interactions, emphasizing its potential significance in cellular communication and signaling pathways mediated by the IGFLR1 receptor. Further investigations into the precise mechanisms and downstream effects of the IGFL1-IGFLR1 interaction will provide valuable insights into the functional roles of this ligand-receptor pair.

Species

Human

Source

HEK293

Tag

C-hFc

Accession

Q6UW32 (A25-S110)

Gene ID
Molecular Construction
N-term
IGFL1 (A25-S110)
Accession # Q6UW32
hFc
C-term
Synonyms
UNQ644; APRG644
AA Sequence

APVAPMTPYLMLCQPHKRCGDKFYDPLQHCCYDDAVVPLARTQTCGNCTFRVCFEQCCPWTFMVKLINQNCDSARTSDDRLCRSVS

Molecular Weight

38.7 kDa

Purity

Greater than 95% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

IGFL1 Protein, Human (HEK293, hFc) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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IGFL1 Protein, Human (HEK293, hFc)
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HY-P700450
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