Wee2 - WEE1 homolog 2 (S. pombe) Gene

Also Known as Wee1B; Gm1065

Species: Mus musculus

Gene Type: protein coding
Gene ID: 381759

Summary

Predicted to enable protein tyrosine kinase activity. Involved in several processes, including female pronucleus assembly; negative regulation of oocyte maturation; and regulation of phosphorylation. Located in cytoplasm and nucleus. Is expressed in 1-cell stage embryo; olfactory epithelium; and ovary. Orthologous to human WEE2 (WEE2 oocyte meiosis inhibiting kinase). [provided by Alliance of Genome Resources, Apr 2022]

Wee2 Products (1)

mRNA Protein Name
NM_201370.2 NP_958758.2 wee1-like protein kinase 2

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in female meiotic nuclear division IMP
IMP: Inferred from mutant phenotype
16169490 MGI
involved in female pronucleus assembly IMP
IMP: Inferred from mutant phenotype
21454751 MGI
involved in negative regulation of cyclin-dependent protein serine/threonine kinase activity IMP
IMP: Inferred from mutant phenotype
21454751 MGI
involved in negative regulation of oocyte maturation IMP
IMP: Inferred from mutant phenotype
16169490 MGI
involved in positive regulation of phosphorylation IDA
IDA: Inferred from direct assay
29606300 MGI
involved in regulation of fertilization IMP
IMP: Inferred from mutant phenotype
29606300 MGI
involved in regulation of meiosis I IMP
IMP: Inferred from mutant phenotype
16169490 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
20083600 MGI
located in nucleus IDA
IDA: Inferred from direct assay
20083600 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

wee1-like protein kinase 2

  • mWee1B

  • wee1-like protein kinase 1B

  • wee1B kinase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-103029 Bosutinib isomer Inhibitor 99.62% Unkown
HY-RS15808 WEE2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Wee2 NCBI NCBI:494551