2. Gene
  3. Mir23b - microRNA 23b Gene

Mir23b - microRNA 23b Gene

  • Gene
  • Agent
  • Ortholog
Mus musculus

Also known as Mirn23b; mmu-mir-23b

Gene ID: 387217 | Gene type: ncRNA

About Mir23b

Summary

MicroRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted MicroRNA stem-loop. [provided by RefSeq, Sep 2009]

Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within cellular response to lipopolysaccharide IDA
IDA: Inferred from direct assay
18762567 MGI
acts upstream of or within long-term synaptic potentiation IEP
IEP: Inferred from expression pattern
25858512 MGI
acts upstream of or within myelination IDA
IDA: Inferred from direct assay
20805985 MGI
acts upstream of or within ossification IDA
IDA: Inferred from direct assay
25751060 MGI
acts upstream of or within positive regulation of angiogenesis IMP
IMP: Inferred from mutant phenotype
21536891 MGI
acts upstream of or within regulation of gene expression IMP
IMP: Inferred from mutant phenotype
21536891 MGI
acts upstream of or within regulation of semaphorin-plexin signaling pathway IMP
IMP: Inferred from mutant phenotype
21536891 MGI
acts upstream of or within retina vasculature development in camera-type eye IMP
IMP: Inferred from mutant phenotype
21536891 MGI
acts upstream of or within sensory perception of sound IEP
IEP: Inferred from expression pattern
23646144 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Related Agents

Pre-clinical Phase
Bioactive Molecules (12)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RI02851 mmu-miR-23b-3p inhibitor 97.75% Unkown
HY-R00482 hsa-miR-23b-5p mimic 96.80% Unkown
HY-R02851 mmu-miR-23b-3p mimic 96.72% Unkown
HY-R02851A mmu-miR-23b-3p agomir 99.26% Unkown
HY-R02852 mmu-miR-23b-5p mimic 94.82% Unkown
HY-RI02852 mmu-miR-23b-5p inhibitor 97.83% Unkown
HY-R00482A hsa-miR-23b-5p agomir / Unkown
HY-R02852A mmu-miR-23b-5p agomir / Unkown
HY-RI00482 hsa-miR-23b-5p inhibitor / Unkown
HY-RI00482A hsa-miR-23b-5p antagomir / Unkown
HY-RI02851A mmu-miR-23b-3p antagomir / Unkown
HY-RI02852A mmu-miR-23b-5p antagomir / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mir23b NCBI NCBI:407011