VWA5A - von Willebrand factor A domain containing 5A Gene

Also Known as BCSC1; BCSC-1; LOH11CR2A

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 4013

About VWA5A

Cytogenetic location: 11q24.2 Genomic coordinates (GRCh38): 11:124,115,450-124,147,721 (from NCBI)

This gene has 6 transcripts (splice variants), 115 orthologues and 11 paralogues. Ubiquitous expression in colon (RPKM 15.2), gall bladder (RPKM 14.6) and 24 other tissues.

Summary

Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

VWA5A Products (3)

mRNA Protein Name
NM_001130142.2 NP_001123614.1 von Willebrand factor A domain-containing protein 5A isoform 1
NM_014622.5 NP_055437.2 von Willebrand factor A domain-containing protein 5A isoform 1
NM_198315.3 NP_938057.1 von Willebrand factor A domain-containing protein 5A isoform 2

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

VWA5A Protein Structure

VIT

VIT: Vault protein inter-alpha-trypsin domain (14 - 130)

VWA_3

VWA_3: von Willebrand factor type A domain (283 - 443)

  • 0
  • 200
  • 400
  • 600
  • 786 a.a.
Protein Preferred Names Protein Names

von Willebrand factor A domain-containing protein 5A

  • breast cancer suppressor candidate 1

VWA5A Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
VWA5A O00534 MEOX2 Homo sapiens Q6FHY5
Y2H Prey Pooling
32296183
Intra
VWA5A O00534 MEOX2 Homo sapiens Q6FHY5
Validated Y2H
32296183
Intra
VWA5A O00534 MEOX2 Homo sapiens Q6FHY5
Y2H Array
32296183
Intra
VWA5A O00534 SPSB1 Homo sapiens Q96BD6
Validated Y2H
32296183
Intra
VWA5A O00534 SPSB1 Homo sapiens Q96BD6
Y2H Array
32296183
Intra
VWA5A O00534 SPSB1 Homo sapiens Q96BD6
Y2H Prey Pooling
32296183
Intra
VWA5A O00534 PRTFDC1 Homo sapiens Q9NRG1
Y2H Prey Pooling
32296183
Intra
VWA5A O00534 PRTFDC1 Homo sapiens Q9NRG1
Validated Y2H
32296183
Intra
VWA5A O00534 PRTFDC1 Homo sapiens Q9NRG1
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Breast Cancer

  • Breast Carcinoma

  • Male Breast Cancer

  • Breast Cancer, Familial

  • Malignant Neoplasm Of Breast

  • Breast Cancer, Susceptibility To

  • Breast Cancer, Early-Onset

  • Malignant Tumor Of Breast

  • Carcinoma Of Male Breast

  • Breast Cancer, Invasive Ductal

  • Breast Cancer, Protection Against

  • Breast Cancer, Somatic

  • Breast Cancer, Male

  • Breast Cancer, Lobular, Somatic

  • Breast Tumor

  • Mammary Cancer

  • Mammary Tumor

  • Malignant Neoplasm Of Male Breast

  • Mammary Carcinoma

  • Male Breast Carcinoma

  • Familial Cancer Of Breast

  • Invasive Ductal Breast Carcinoma

  • Breast Cancer Susceptibility

  • Breast Cancer, Male, Susceptibility To

  • Breast Cancer, Early-Onset, Susceptibility To

  • Malignant Tumor Of The Breast

  • Mammary Neoplasm

  • Primary Breast Cancer

  • Neoplasm Of Male Breast

  • Carcinoma Of Breast

  • Breast Cancer In Men

  • Familial Breast Cancer

  • Cancer Of Breast

  • BC

  • Breast Cancer Familial

  • Breast Cancer Familial Male

  • Breast Cancer, Familial Male

  • Breast Male Carcinoma

  • Breast Neoplasms

  • Breast Neoplasms, Male

  • Mammary Tumors

  • Mammary Carcinomas

  • Cancer, Breast

  • Cancer, Breast, Susceptibility

  • Invasive Breast Ductal Carcinoma

  • Breast Neoplasm

  • Susceptibility To Breast Cancer

  • Mammary Neoplasms

  • Animal Mammary Neoplasms

  • Primary Malignant Neoplasm Of Breast

  • Infiltrating Ductal Carcinoma Of Breast

  • Infiltrating Duct Carcinoma Of Unspecified Site

  • Infiltrating Ductular Carcinoma Of Unspecified Site

  • Invasive Breast Carcinoma Of No Special Type

  • Microinvasive Carcinoma Of Breast

  • Carcinoma With Apocrine Differentiation
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15728 VWA5A Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus VWA5A VGNC VGNC:81094
Mus musculus VWA5A MGD MGI:1915026
Bos taurus VWA5A VGNC VGNC:36853
Macaca mulatta VWA5A VGNC VGNC:79963
Canis familiaris VWA5A VGNC VGNC:48322
Rattus norvegicus VWA5A RGD RGD:735145
Others VWA5A NCBI