2. Gene
  3. LSAMP - limbic system associated membrane protein Gene

LSAMP - limbic system associated membrane protein Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as LAMP; IGLON3

Gene ID: 4045 | Gene type: protein coding

About LSAMP

Cytogenetic location: 3q13.31 Genomic coordinates (GRCh38): 3:115,802,374-116,445,487 (from NCBI)

This gene has 7 transcripts (splice variants), 219 orthologues and 5 paralogues. Biased expression in brain (RPKM 19.9), prostate (RPKM 5.4) and 9 other tissues.

Summary

This gene encodes a member of the immunoglobulin LAMP, OBCAM and neurotrimin (IgLON) family of proteins. The encoded preproprotein is proteolytically processed to generate a neuronal surface glycoprotein. This protein may act as a selective homophilic adhesion molecule during axon guidance and neuronal growth in the developing limbic system. The encoded protein may also function as a tumor suppressor and may play a role in neuropsychiatric disorders. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]

LSAMP Products(2)

mRNA Protein Name
NM_001318915.2 NP_001305844.1 limbic system-associated membrane protein isoform 2 precursor
NM_002338.5 NP_002329.2 limbic system-associated membrane protein isoform 1 preproprotein

LSAMP Protein Structure

I-set

I-set: Immunoglobulin I-set domain (34 - 128)

I-set

I-set: Immunoglobulin I-set domain (132 - 215)

I-set

I-set: Immunoglobulin I-set domain (222 - 305)

  • 0
  • 100
  • 200
  • 300
  • 338 a.a.
Protein Preferred Names Protein Names

limbic system-associated membrane protein

IgLON family member 3

Recombinant LSAMP Proteins

Cat. No. Product Name Accession Purity
HY-P70414 LSAMP Protein, Human (HEK293, His) Q13449 (V29-N315) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07850 LSAMP Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus LSAMP VGNC VGNC:68095
Rattus norvegicus LSAMP RGD RGD:71102
Canis familiaris LSAMP VGNC VGNC:42836
Bos taurus LSAMP VGNC VGNC:106809
Macaca mulatta LSAMP VGNC VGNC:74450
Mus musculus LSAMP MGD MGI:1261760
Others LSAMP NCBI