CENPV - centromere protein V Gene

Homo sapiens

Also known as p30; PRR6; CENP-V; 3110013H01Rik

Gene ID: 201161 | Gene type: protein coding

About CENPV

Cytogenetic location: 17p11.2 Genomic coordinates (GRCh38): 17:16,342,537-16,353,469 (from NCBI)

This gene has 7 transcripts (splice variants), 180 orthologues and 3 paralogues. Broad expression in small intestine (RPKM 17.0), duodenum (RPKM 16.5) and 25 other tissues.

Summary

Predicted to enable carbon-sulfur lyase activity and metal ion binding activity. Involved in pericentric heterochromatin assembly; positive regulation of cytokinesis; and regulation of chromosome organization. Acts upstream of or within ameboidal-type cell migration. Located in several cellular components, including midbody; nucleus; and spindle midzone. [provided by Alliance of Genome Resources, Apr 2022]

CENPV Products(1)

mRNA	Protein	Name
NM_181716.3	NP_859067.2	centromere protein V

CENPV Protein Structure

GFA

0
100
200
272 a.a.

Protein Preferred Names

Protein Names

centromere protein V

nuclear protein p30

Related Diseases

Diseases

Alias

Histoplasmosis Retinitis

Histoplasmosis With Retinitis

Central Nervous System Hemangioma

Hemangioma Of Cns

Hemangioma Of The Central Nervous System

Intracranial Primitive Neuroectodermal Tumor

Intracranial Pnet

Intracranial Primitive Neuroectodermal Neoplasm

Diffuse Glomerulonephritis

Glomerulonephritis Diffuse

T-Cell Adult Acute Lymphocytic Leukemia

Acute Adult T-Cell Leukemia-Lymphoma	Adult Precursor T Lymphoblastic Leukemia
Atll	T-Cell Adult Acute Lymphoblastic Leukemia

Askin'S Tumor

Askin Tumor	Askin Tumour
Askin'S Tumour

Extraosseous Ewing Sarcoma

Extraosseous Ewing'S Sarcoma	Extraosseous Ewing'S Sarcoma/Peripheral Primitive Neuroectodermal Tumor
Extraskeletal Ewing Sarcom	Sarcoma Extraosseous Ewings
Extraosseous Ewings Sarcoma-Primitive Neuroepithelial Tumor

Adult T-Cell Leukemia/Lymphoma

Adult T-Cell Leukemia	Atll
Adult T-Cell Leukaemia	Adult T-Cell Leukaemia/Lymphoma
Adult T-Cell Lymphoma	T Cell Leukemia Lymphoma Adult
Leukemia-Lymphoma, Adult T-Cell	Leukemia, T-Cell
Adult T-Cell Lymphoma/Leukemia

Ehrlichiosis

Human Ehrlichiosis	He
Hey

Tropical Spastic Paraparesis

Tropical Spastic Paraplegia	Ham/Tsp
Htlv-Associated Myelopathy	Tropical Spastic Paralysis
Htlv-1 Associated Myelopathy/Tropical Spastic Paraparesis	Human T-Cell Leukemia Virus Type 1 Associated Myelopathy/Tropical Spastic Paraparesis
Htlv-1-Associated Myelopathy/Tropical Spastic Paraparesis	Human T-Lymphotropic Virus Type I-Associated Myelopathy/Tropical Spastic Paraparesis
Human T-Lymphotropic Virus Type-1-Associated Myelopathy/Tropical Spastic Paraparesis	Tsp
Paraparesis Tropical Spastic	Paraparesis, Tropical Spastic

Adult Acute Lymphocytic Leukemia

Adult Acute Lymphoid Leukemia

Adult All

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02493	CENPV Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	CENPV	MGD	MGI:1920389
Rattus norvegicus	CENPV	RGD	RGD:1565681
Bos taurus	CENPV	VGNC	VGNC:107269
Canis familiaris	CENPV	VGNC	VGNC:53316
Macaca mulatta	CENPV	VGNC	VGNC:99137

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