TGFBR1 - transforming growth factor beta receptor 1 Gene

Species: Canis lupus familiaris (sub-species: familiaris)

Gene Type: protein coding
Gene ID: 481628

About TGFBR1

Primary_assembly 11: 57,272,651-57,331,431 forward strand.ROS_Cfam_1.0:CM025110.1

This gene has 1 transcript (splice variant), 236 orthologues and 10 paralogues.

TGFBR1 Products (2)

mRNA Protein Name
XM_038682263.1 XP_038538191.1 TGF-beta receptor type-1 isoform X2
XM_038682262.1 XP_038538190.1 TGF-beta receptor type-1 isoform X1

TGFBR1 Protein Structure

Activin_recp

Activin_recp: pfam01064 (30 - 106)

TGF_beta_GS

TGF_beta_GS: pfam08515 (176 - 203)

STKc_TGFbR1_ACVR1b_ACVR1c

STKc_TGFbR1_ACVR1b_ACVR1c: cd14143 (209 - 496)

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  • 504 a.a.
Protein Preferred Names Protein Names

TGF-beta receptor type-1

  • transforming growth factor beta type I receptor

  • transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kDa)

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-136244 PF-06952229 Inhibitor 99.92% Phase 1

Pre-clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-164793 TGFBR1-IN-2 / Unkown
HY-122856 AZ12601011 Inhibitor 99.78% Unkown
HY-N7694 Isotoosendanin 99.51% Unkown
HY-123900 AZ12799734 Inhibitor 98.67% Unkown
HY-RS14444 TGFBR1 Human Pre-designed siRNA Set A / Unkown
HY-RS14445 Tgfbr1 Mouse Pre-designed siRNA Set A / Unkown
HY-RS14446 TGFBR1 Rat Pre-designed siRNA Set A / Unkown
HY-174531 Human TGFBR1 mRNA / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens TGFBR1 NCBI NCBI:7046