Bex2 - brain expressed X-linked 2 Gene

Rattus norvegicus

Also known as Bex; Bex1; Bex1h

Gene ID: 501625 | Gene type: protein coding

About Bex2

Summary

Predicted to enable signaling receptor binding activity. Acts upstream of or within negative regulation of neuron differentiation; neurotrophin Trk Receptor signaling pathway; and positive regulation of neuroblast proliferation. Located in cytoplasm and nucleus. Orthologous to human BEX1 (brain expressed X-linked 1) and BEX2 (brain expressed X-linked 2). [provided by Alliance of Genome Resources, Apr 2022]

Bex2 Products(1)

mRNA	Protein	Name
NM_001037365.2	NP_001032442.1	protein BEX2

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	16498402	RGD

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within negative regulation of neuron differentiation	IDA IDA: Inferred from direct assay	16498402	RGD
acts upstream of or within positive regulation of neuroblast proliferation	IDA IDA: Inferred from direct assay	16498402	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in cytoplasm	IDA IDA: Inferred from direct assay	16498402	RGD
located in nucleus	IDA IDA: Inferred from direct assay	15958283	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

protein BEX2

EG2RVC	brain expressed gene 1
brain expressed, X-linked 1	brain-expressed X-linked protein 1 homolog
brain-expressed X-linked protein 2 homolog	protein BEX1

Bex2 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	Bex1	Q3MKQ2	Ngfr	Rattus norvegicus	P07174	T7 Phage	16498402
Intra	Bex1	Q3MKQ2	Ngfr	Rattus norvegicus	P07174	Anti Bait CoIP	16498402
Intra	Bex1	Q3MKQ2	Ngfr	Rattus norvegicus	P07174	Anti Tag CoIP	16498402

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01481	BEX2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Bex2	NCBI	NCBI:84707

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