TUBE1 - tubulin epsilon 1 Gene
Also Known as TUBE; dJ142L7.2
Species: Homo sapiens
About TUBE1
This gene has 11 transcripts (splice variants), 209 orthologues and 23 paralogues. Broad expression in testis (RPKM 21.9), endometrium (RPKM 10.2) and 25 other tissues.
Summary
This gene encodes a member of the tubulin superfamily. This protein localizes to the centriolar sub-distal appendages that are associated with the older of the two centrioles after centrosome duplication. This protein plays a central role in organization of the microtubules during centriole duplication. A pseudogene of this gene is found on chromosome 5.[provided by RefSeq, Jan 2009]
TUBE1 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_016262.5 | NP_057346.1 | tubulin epsilon chain |
TUBE1 Protein Structure
Tubulin: Tubulin/FtsZ family, GTPase domain (5 - 220)
Tubulin_C: Tubulin C-terminal domain (294 - 413)
- 0
- 100
- 200
- 300
- 400
- 475 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
tubulin epsilon chain |
|
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Bladder Exstrophy |
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-D1247 | Hydroxynaphthol Blue | 95.0% | Unkown | |
| HY-147186 | 5,5'-Difluoro BAPTA | / | Unkown | |
| HY-D1640 | 5',5-Difluoro BAPTA tetrapotassium | / | Unkown | |
| HY-RS15260 | TUBE1 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Bos taurus | TUBE1 | VGNC | VGNC:36511 |
| Mus musculus | TUBE1 | MGD | MGI:1919174 |
| Canis familiaris | TUBE1 | VGNC | VGNC:54383 |
| Rattus norvegicus | TUBE1 | RGD | RGD:1306048 |
| Macaca mulatta | TUBE1 | VGNC | VGNC:79284 |
| Felis catus | TUBE1 | VGNC | VGNC:66703 |
| Others | TUBE1 | NCBI |
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