Chrnd - cholinergic receptor nicotinic delta subunit Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 54240

Summary

Enables acetylcholine-gated cation-selective channel activity. Involved in cation transport and skeletal muscle contraction. Part of acetylcholine-gated channel complex. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 3A; congenital myasthenic syndrome 3B; and congenital myasthenic syndrome 3C. Orthologous to human CHRND (cholinergic receptor nicotinic delta subunit). [provided by Alliance of Genome Resources, Apr 2022]

Chrnd Products (1)

mRNA Protein Name
NM_019298.1 NP_062171.1 acetylcholine receptor subunit delta precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables acetylcholine-gated monoatomic cation-selective channel activity IDA
IDA: Inferred from direct assay
1702709 RGD
enables ligand-gated monoatomic ion channel activity IDA
IDA: Inferred from direct assay
1702709 RGD
Biological Process GO Annotation Evidence References Source
involved in monoatomic cation transport IDA
IDA: Inferred from direct assay
22461452 RGD
involved in skeletal muscle contraction IDA
IDA: Inferred from direct assay
22461452 RGD
Cellular Component GO Annotation Evidence References Source
part of acetylcholine-gated channel complex IDA
IDA: Inferred from direct assay
22461452 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

acetylcholine receptor subunit delta

  • cholinergic receptor, nicotinic delta

  • cholinergic receptor, nicotinic, delta (muscle)

  • cholinergic receptor, nicotinic, delta polypeptide

  • nicotinic acetylcholine receptor delta-subunit

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02678 CHRND Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22439 Chrnd Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28962 Chrnd Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Chrnd NCBI NCBI:1144