Pdpn - podoplanin Gene

Also Known as E11; Gp38; OTS-8; RTI40; T1-alpha

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 54320

Summary

Predicted to enable chaperone binding activity; chemokine binding activity; and signaling receptor binding activity. Involved in several processes, including lung development; positive regulation of platelet activation; and response to hyperoxia. Acts upstream of or within cell adhesion; positive regulation of cell migration; and tube morphogenesis. Located in apical plasma membrane. Biomarker of adult respiratory distress syndrome; Bacterial pneumonia; nephrosis; and oligohydramnios. Orthologous to human PDPN (podoplanin). [provided by Alliance of Genome Resources, Apr 2022]

Pdpn Products (1)

mRNA Protein Name
NM_019358.2 NP_062231.2 podoplanin precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within cell adhesion IDA
IDA: Inferred from direct assay
12853470 RGD
involved in lung development IEP
IEP: Inferred from expression pattern
8652186 RGD
involved in nervous system development IEP
IEP: Inferred from expression pattern
8652186 RGD
acts upstream of or within positive regulation of cell migration IDA
IDA: Inferred from direct assay
12853470 RGD
involved in positive regulation of platelet activation IMP
IMP: Inferred from mutant phenotype
16979138 RGD
involved in response to hyperoxia IEP
IEP: Inferred from expression pattern
12922978 RGD
acts upstream of or within tube morphogenesis IDA
IDA: Inferred from direct assay
12853470 RGD
Cellular Component GO Annotation Evidence References Source
located in apical plasma membrane IDA
IDA: Inferred from direct assay
7851650 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

podoplanin

  • E11 antigen epitope

  • RTI140

  • T1A

  • epithelial cell surface transmembrane protein antigen

  • glycoprotein 38

  • pulmonary type I alveolar epithelial cell transmembrane differentiation marker

  • type I cell 40 kDa protein

Recombinant Pdpn Proteins

Cat. No. Product Name Accession Purity
HY-P74624 Podoplanin Protein, Rat (HEK293, hFc) Q64294 (G23-L135) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS17024 Pdpn Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-E70294 N-Acetylgalactosaminyltransferase 13 / Unkown
HY-RS10288 PDPN Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23467 Pdpn Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pdpn NCBI NCBI:10630