Cacng4 - calcium channel, voltage-dependent, gamma subunit 4 Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 54377

Summary

Predicted to enable Calcium Channel regulator activity; ionotropic glutamate receptor binding activity; and voltage-gated Calcium Channel activity. Involved in regulation of AMPA Receptor activity and regulation of postsynaptic neurotransmitter receptor activity. Acts upstream of or within transmission of nerve impulse. Located in glutamatergic synapse and somatodendritic compartment. Part of AMPA glutamate receptor complex. Is expressed in several structures, including central nervous system; eye; genitourinary system; gut; and respiratory system. Orthologous to human CACNG4 (calcium voltage-gated channel auxiliary subunit gamma 4). [provided by Alliance of Genome Resources, Apr 2022]

Cacng4 Products (1)

mRNA Protein Name
NM_019431.4 NP_062304.1 voltage-dependent calcium channel gamma-4 subunit

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in regulation of AMPA receptor activity IMP
IMP: Inferred from mutant phenotype
17880894 MGI
involved in regulation of postsynaptic neurotransmitter receptor activity IDA
IDA: Inferred from direct assay
17880893 MGI
involved in regulation of postsynaptic neurotransmitter receptor activity IMP
IMP: Inferred from mutant phenotype
17880893 MGI
acts upstream of or within transmission of nerve impulse IGI
IGI: Inferred from genetic interaction
15677329 MGI
Cellular Component GO Annotation Evidence References Source
part of AMPA glutamate receptor complex IDA
IDA: Inferred from direct assay
22632720 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
17880893 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
17880893 MGI
located in somatodendritic compartment IDA
IDA: Inferred from direct assay
18341993 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

voltage-dependent calcium channel gamma-4 subunit

  • TARP gamma-4

  • neuronal voltage-gated calcium channel gamma-4 subunit

  • transmembrane AMPAR regulatory protein gamma-4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01812 CACNG4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cacng4 NCBI NCBI:27092