Ywhab - tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide Gene

Also Known as 14-3-3b; 1300003C17Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 54401

Summary

Enables protein domain specific binding activity. Acts upstream of or within protein targeting. Predicted to be located in cytosol; nucleus; and perinuclear region of cytoplasm. Predicted to be part of transcription repressor complex. Predicted to be active in cytoplasm. Is expressed in several structures, including genitourinary system; nervous system; palatal shelf; retina layer; and thymus. Orthologous to human YWHAB (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta). [provided by Alliance of Genome Resources, Apr 2022]

Ywhab Products (1)

mRNA Protein Name
NM_018753.6 NP_061223.2 14-3-3 protein beta/alpha

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
12937170 MGI
enables protein domain specific binding IDA
IDA: Inferred from direct assay
12446771 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within protein targeting IDA
IDA: Inferred from direct assay
12446771 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

14-3-3 protein beta/alpha

  • 14-3-3 protein beta

  • KCIP-1

  • protein kinase C inhibitor protein 1

  • tyrosine 3/tryptophan 5 -monooxygenase activation protein, beta polypeptide

Ywhab Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Ywhab Q9CQV8 Prkce Mus musculus P16054
Pull Down
18237277
Intra
Ywhab Q9CQV8 Prkce Mus musculus P16054
Pull Down
18604201
Intra
Ywhab Q9CQV8 Synpo2 Mus musculus Q91YE8
CoIP
15883195
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant Ywhab Proteins

Cat. No. Product Name Accession Purity
HY-P71850 KCIP-1 Protein, Mouse (P.pastoris, His) Q9CQV8-1 (M1-N246) ≥ 90%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15940 YWHAB Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19757 Ywhab Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26254 Ywhab Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ywhab NCBI NCBI:7529