Ubqln2 - ubiquilin 2 Gene

Also Known as Dsk2; Chap1; Plic2; Plic-2; HRIHFB2157

Species: Mus musculus

Gene Type: protein coding
Gene ID: 54609

Summary

Predicted to enable identical protein binding activity and polyubiquitin modification-dependent protein binding activity. Predicted to be involved in several processes, including negative regulation of receptor-mediated endocytosis; regulation of cellular catabolic process; and ubiquitin-dependent ERAD pathway. Predicted to act upstream of or within Autophagy. Predicted to be located in cytoplasm and plasma membrane. Predicted to be active in cytosol. Is expressed in telencephalon. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis and amyotrophic lateral sclerosis type 15. Orthologous to human UBQLN2 (ubiquilin 2). [provided by Alliance of Genome Resources, Apr 2022]

Ubqln2 Products (1)

mRNA Protein Name
NM_018798.2 NP_061268.2 ubiquilin-2

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
24549040 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ubiquilin-2

  • Ubiquitin-related protein

  • protein linking IAP with cytoskeleton 2

  • ubiquitin-like product Chap1/Dsk2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15384 UBQLN2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ubqln2 NCBI NCBI:29978