SLC25A40 - solute carrier family 25 member 40 Gene

Also Known as MCFP

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 55972

About SLC25A40

Cytogenetic location: 7q21.12 Genomic coordinates (GRCh38): 7:87,833,568-87,876,360 (from NCBI)

This gene has 8 transcripts (splice variants), 132 orthologues and 49 paralogues. Ubiquitous expression in lymph node (RPKM 7.5), appendix (RPKM 7.3) and 25 other tissues.

Summary

SLC25A40 belongs to the SLC25 family of mitochondrial carrier proteins (Haitina et al., 2006 [PubMed 16949250]).[supplied by OMIM, Mar 2008]

SLC25A40 Products (1)

mRNA Protein Name
NM_018843.4 NP_061331.2 probable mitochondrial glutathione transporter SLC25A40

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables glutathione transmembrane transporter activity IMP
IMP: Inferred from mutant phenotype
34707288 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
33961781 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SLC25A40 Protein Structure

Mito_carr

Mito_carr: Mitochondrial carrier protein (13 - 134)

Mito_carr

Mito_carr: Mitochondrial carrier protein (144 - 227)

Mito_carr

Mito_carr: Mitochondrial carrier protein (233 - 331)

  • 0
  • 100
  • 200
  • 300
  • 338 a.a.
Protein Preferred Names Protein Names

probable mitochondrial glutathione transporter SLC25A40

  • mitochondrial carrier family protein

SLC25A40 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
SLC25A40 Q8TBP6 COL1A1 Homo sapiens P02452
Anti Tag CoIP
33961781
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13123 SLC25A40 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris SLC25A40 VGNC VGNC:54795
Macaca mulatta SLC25A40 VGNC VGNC:77583
Rattus norvegicus SLC25A40 RGD RGD:1308774
Felis catus SLC25A40 VGNC VGNC:80718
Mus musculus SLC25A40 MGD MGI:2442486
Others SLC25A40 NCBI