Slc2a8 - solute carrier family 2, (facilitated glucose transporter), member 8 Gene

Also Known as GLUT8; GlutX1; D2Ertd44e

Species: Mus musculus

Gene Type: protein coding
Gene ID: 56017

Summary

Enables dehydroascorbic acid transmembrane transporter activity; glucose binding activity; and hexose transmembrane transporter activity. Involved in dehydroascorbic acid transport; fructose transmembrane transport; and glucose transmembrane transport. Acts upstream of or within Insulin Receptor signaling pathway and response to hypoxia. Is integral component of plasma membrane. Is expressed in several structures, including adipose tissue; gut; liver; placenta; and spleen. Orthologous to human SLC2A8 (solute carrier family 2 member 8). [provided by Alliance of Genome Resources, Apr 2022]

Slc2a8 Products (2)

mRNA Protein Name
NM_001356409.1 NP_001343338.1 solute carrier family 2, facilitated glucose transporter member 8 isoform 2
NM_019488.5 NP_062361.1 solute carrier family 2, facilitated glucose transporter member 8 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables D-glucose binding IDA
IDA: Inferred from direct assay
10821868 MGI
enables D-glucose transmembrane transporter activity IDA
IDA: Inferred from direct assay
10821868 MGI
enables dehydroascorbic acid transmembrane transporter activity IDA
IDA: Inferred from direct assay
23396969 MGI
enables fructose transmembrane transporter activity IDA
IDA: Inferred from direct assay
23396969 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within D-glucose transmembrane transport IDA
IDA: Inferred from direct assay
10821868 MGI
involved in D-glucose transmembrane transport IDA
IDA: Inferred from direct assay
23396969 MGI
involved in dehydroascorbic acid transport IDA
IDA: Inferred from direct assay
23396969 MGI
involved in fructose transmembrane transport IDA
IDA: Inferred from direct assay
23396969 MGI
acts upstream of or within insulin receptor signaling pathway IDA
IDA: Inferred from direct assay
10860996 MGI
acts upstream of or within response to hypoxia IDA
IDA: Inferred from direct assay
11689004 MGI
Cellular Component GO Annotation Evidence References Source
located in plasma membrane IDA
IDA: Inferred from direct assay
10821868 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

solute carrier family 2, facilitated glucose transporter member 8

  • GLUT-8

  • glucose transporter X1

  • glucose transporter type 8

  • glucose transporter type X1

  • intestinal GLUT8 transporter

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-139047 SW157765 Inhibitor 98.08% Unkown
HY-RS13176 SLC2A8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
Bioactive MoleculesInhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P990674 VB1-050 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc2a8 NCBI NCBI:29988