Gtpbp2 - GTP binding protein 2 Gene

Also Known as nmf205

Species: Mus musculus

Gene Type: protein coding
Gene ID: 56055

Summary

Predicted to enable GTP binding activity; identical protein binding activity; and translation elongation factor activity. Acts upstream of or within nuclear-transcribed mRNA catabolic process, no-go decay and rescue of stalled ribosome. Is expressed in central nervous system and eye. Orthologous to human GTPBP2 (GTP binding protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Gtpbp2 Products (10)

mRNA Protein Name
NM_001145979.2 NP_001139451.1 GTP-binding protein 2 isoform 2
NM_001357745.2 NP_001344674.1 GTP-binding protein 2 isoform 2
NM_001410154.1 NP_001397083.1 GTP-binding protein 2 isoform 1
NM_001410155.1 NP_001397084.1 GTP-binding protein 2 isoform 3
NM_001410156.1 NP_001397085.1 GTP-binding protein 2 isoform 2
NM_001410157.1 NP_001397086.1 GTP-binding protein 2 isoform 2
NM_001410158.1 NP_001397087.1 GTP-binding protein 2 isoform 2
NM_001410159.1 NP_001397088.1 GTP-binding protein 2 isoform 4
NM_001410160.1 NP_001397089.1 GTP-binding protein 2 isoform 5
NM_019581.4 NP_062527.2 GTP-binding protein 2 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25061210 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within nuclear-transcribed mRNA catabolic process, no-go decay IMP
IMP: Inferred from mutant phenotype
25061210 MGI
acts upstream of or within rescue of stalled ribosome IMP
IMP: Inferred from mutant phenotype
25061210 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

GTP-binding protein 2

  • GTP-binding-like protein 2

Gtpbp2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Gtpbp2 Q3UJK4 Pelo Mus musculus Q80X73
Pull Down
25061210
Intra
Gtpbp2 Q3UJK4 Pelo Mus musculus Q80X73
Anti Tag CoIP
25061210
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05909 GTPBP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gtpbp2 NCBI NCBI:54676