Olfm1 - olfactomedin 1 Gene

Also Known as AMY; Noe1; OlfA; Pancortin; Pancortin3

Species: Mus musculus

Gene Type: protein coding
Gene ID: 56177

Summary

Enables amyloid-beta binding activity and identical protein binding activity. Involved in neuronal signal transduction and regulation of axon extension. Acts upstream of or within negative regulation of amyloid-beta formation and negative regulation of neuron migration. Located in several cellular components, including axonal growth cone; neuronal cell body; and synaptic membrane. Part of AMPA glutamate receptor complex. Is active in glutamatergic synapse. Is extrinsic component of synaptic membrane. Is expressed in several structures, including central nervous system; embryo ectoderm; peripheral nervous system ganglion; sensory organ; and tooth. Orthologous to human OLFM1 (olfactomedin 1). [provided by Alliance of Genome Resources, Apr 2022]

Olfm1 Products (4)

mRNA Protein Name
NM_001038612.1 NP_001033701.1 noelin isoform b precursor
NM_001038613.1 NP_001033702.1 noelin isoform c precursor
NM_001038614.1 NP_001033703.1 noelin isoform d precursor
NM_019498.2 NP_062371.2 noelin isoform a precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
15927402 MGI
Biological Process GO Annotation Evidence References Source
involved in neuronal signal transduction IDA
IDA: Inferred from direct assay
22923615 MGI
involved in regulation of axon extension IDA
IDA: Inferred from direct assay
22923615 MGI
Cellular Component GO Annotation Evidence References Source
part of AMPA glutamate receptor complex IDA
IDA: Inferred from direct assay
22632720 MGI
located in axon IDA
IDA: Inferred from direct assay
22923615 MGI
located in axonal growth cone IDA
IDA: Inferred from direct assay
22923615 MGI
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
17265465 MGI
located in extracellular space IDA
IDA: Inferred from direct assay
22923615 MGI
is active in extrinsic component of postsynaptic density membrane IDA
IDA: Inferred from direct assay
30067977 MGI
is active in extrinsic component of synaptic membrane IDA
IDA: Inferred from direct assay
25218043 MGI
is active in extrinsic component of synaptic membrane IEP
IEP: Inferred from expression pattern
25218043 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
25218043 MGI
is active in glutamatergic synapse IEP
IEP: Inferred from expression pattern
25218043 MGI
located in neuronal cell body IDA
IDA: Inferred from direct assay
22923615 MGI
located in synaptic membrane IDA
IDA: Inferred from direct assay
25218043 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

noelin

  • Noelin 1

  • Noelin 2

  • Pancortin 1-4

  • neuronal olfactomedin-related ER localized protein

  • olfactomedin related ER localized protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09770 OLFM1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21677 Olfm1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28195 Olfm1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Olfm1 NCBI NCBI:10439