Cyp4f1 - cytochrome P450, family 4, subfamily f, polypeptide 1 Gene

Also Known as Cyp4f2; Cyp4f14

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 56266

Summary

Enables several functions, including arachidonic acid binding activity; heme binding activity; and leukotriene-B4 20-monooxygenase activity. Involved in leukotriene B4 catabolic process; omega-hydroxylase P450 pathway; and response to toxic substance. Located in intracellular membrane-bounded organelle. Biomarker of hypertension. Orthologous to several human genes including CYP4F2 (Cytochrome P450 family 4 subfamily F member 2). [provided by Alliance of Genome Resources, Apr 2022]

Cyp4f1 Products (1)

mRNA Protein Name
NM_019623.2 NP_062569.2 cytochrome P450 4F1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables arachidonate binding IDA
IDA: Inferred from direct assay
14634044 RGD
enables arachidonate monooxygenase activity IDA
IDA: Inferred from direct assay
14634044 RGD
enables heme binding IDA
IDA: Inferred from direct assay
11980497 RGD
enables leukotriene-B4 20-monooxygenase activity IDA
IDA: Inferred from direct assay
10486137 RGD
Biological Process GO Annotation Evidence References Source
involved in arachidonate metabolic process IDA
IDA: Inferred from direct assay
16415532 RGD
involved in icosanoid metabolic process IDA
IDA: Inferred from direct assay
10486137 RGD
involved in leukotriene B4 catabolic process IDA
IDA: Inferred from direct assay
10486137 RGD
involved in omega-hydroxylase P450 pathway IDA
IDA: Inferred from direct assay
14634044 RGD
involved in response to toxic substance IEP
IEP: Inferred from expression pattern
9744542 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cytochrome P450 4F1

  • CYPIVF1

  • P450-A3

  • cytochrome P450, family 4, subfamily F, polypeptide 2

  • cytochrome P450, subfamily IVF, polypeptide 14 (leukotriene B4 omega hydroxylase)

  • cytochrome P450-A3

  • leukotriene-B4 20-monooxygenase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03478 CYP4F11 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS03479 CYP4F12 Human Pre-designed siRNA Set A Pre-designed Set / Unkown