Timm22 - translocase of inner mitochondrial membrane 22 Gene

Also Known as Tim22

Species: Mus musculus

Gene Type: protein coding
Gene ID: 56322

Summary

Predicted to enable mitochondrion targeting sequence binding activity and protein transmembrane transporter activity. Predicted to be involved in protein insertion into mitochondrial inner membrane. Predicted to act upstream of or within protein transport. Located in mitochondrion. Is expressed in several structures, including alimentary system; brain; cardiovascular system; egg cylinder; and genitourinary system. Human ortholog(s) of this gene implicated in combined Oxidative Phosphorylation deficiency 43. Orthologous to human TIMM22 (translocase of inner mitochondrial membrane 22). [provided by Alliance of Genome Resources, Apr 2022]

Timm22 Products (3)

mRNA Protein Name
NM_001291161.1 NP_001278090.1 mitochondrial import inner membrane translocase subunit Tim22 isoform 3
NM_019818.5 NP_062792.2 mitochondrial import inner membrane translocase subunit Tim22 isoform 1
NM_023355.2 NP_075844.1 mitochondrial import inner membrane translocase subunit Tim22 isoform 2

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
11591653 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mitochondrial import inner membrane translocase subunit Tim22

  • preprotein translocase

  • translocase of inner mitochondrial membrane 22 homolog

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14530 TIMM22 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Timm22 NCBI NCBI:29928