Adam15 - ADAM metallopeptidase domain 15 Gene

Also Known as MDC15; tMDCVI

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 57025

Summary

Predicted to enable SH3 domain binding activity; Integrin binding activity; and metallopeptidase activity. Involved in male gonad development; response to hypobaric hypoxia; and tissue regeneration. Predicted to be located in cell surface and extracellular exosome. Predicted to be active in extracellular space. Orthologous to human ADAM15 (ADAM metallopeptidase domain 15). [provided by Alliance of Genome Resources, Apr 2022]

Adam15 Products (3)

mRNA Protein Name
NM_001399128.1 NP_001386057.1 disintegrin and metalloproteinase domain-containing protein 15 isoform 1 precursor
NM_001399129.1 NP_001386058.1 disintegrin and metalloproteinase domain-containing protein 15 isoform 2 precursor
NM_020308.2 NP_064704.1 disintegrin and metalloproteinase domain-containing protein 15 isoform 3 precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in male gonad development IEP
IEP: Inferred from expression pattern
12815633 RGD
involved in response to hypobaric hypoxia IEP
IEP: Inferred from expression pattern
22230263 RGD
involved in tissue regeneration IEP
IEP: Inferred from expression pattern
11102971 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

disintegrin and metalloproteinase domain-containing protein 15

  • ADAM 15

  • CRII-7

  • MDC-15

  • a disintegrin and metallopeptidase domain 15 (metargidin)

  • a disintegrin and metalloproteinase domain 15 (metargidin)

  • metalloprotease RGD disintegrin protein

  • metalloproteinase-like, disintegrin-like, and cysteine-rich protein 15

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-N0863 Methyl protodioscin 99.67% Unkown
HY-RS00270 ADAM15 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18692 Adam15 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25179 Adam15 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Adam15 NCBI NCBI:8751