PCNP - PEST proteolytic signal containing nuclear protein Gene

Homo sapiens

Gene ID: 57092 | Gene type: protein coding

About PCNP

Cytogenetic location: 3q12.3 Genomic coordinates (GRCh38): 3:101,574,094-101,594,465 (from NCBI)

This gene has 8 transcripts (splice variants) and 187 orthologues. Ubiquitous expression in ovary (RPKM 78.0), thyroid (RPKM 65.5) and 25 other tissues.

Summary

Involved in proteasome-mediated ubiquitin-dependent protein catabolic process and protein ubiquitination. Located in nuclear body. [provided by Alliance of Genome Resources, Apr 2022]

PCNP Products(7)

mRNA	Protein	Name
NM_001320395.1	NP_001307324.1	PEST proteolytic signal-containing nuclear protein isoform b
NM_001320397.1	NP_001307326.1	PEST proteolytic signal-containing nuclear protein isoform c
NM_001320398.1	NP_001307327.1	PEST proteolytic signal-containing nuclear protein isoform d
NM_001320399.1	NP_001307328.1	PEST proteolytic signal-containing nuclear protein isoform e
NM_001320400.1	NP_001307329.1	PEST proteolytic signal-containing nuclear protein isoform f
NM_001320401.1	NP_001307330.1	PEST proteolytic signal-containing nuclear protein isoform g
NM_020357.3	NP_065090.1	PEST proteolytic signal-containing nuclear protein isoform a

PCNP Protein Structure

PCNP

0
100
178 a.a.

Protein Preferred Names

Protein Names

PEST proteolytic signal-containing nuclear protein

PEST-containing nuclear protein

Related Diseases

Diseases

Alias

Venezuelan Hemorrhagic Fever

Guanarito Hemorrhagic Fever

Vehf - [Venezuelan Haemorrhagic Fever]

Hereditary Lymphedema I

Lymphedema	Hereditary Lymphedema Type I
Congenital Primary Lymphedema	Lmph1
Milroy Disease	Nonne-Milroy Lymphedema
Pcl	Lymphedema Hereditary Type 1

Hereditary Lymphedema

Milroy Disease

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10160	PCNP Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	PCNP	RGD	RGD:1563775
Bos taurus	PCNP	VGNC	VGNC:32636
Felis catus	PCNP	VGNC	VGNC:102801
Canis familiaris	PCNP	VGNC	VGNC:44311
Mus musculus	PCNP	MGD	MGI:1923552
Macaca mulatta	PCNP	VGNC	VGNC:84059