MC38 SLP Adpgk
Based on 1 Customer Validation
MC38 SLP Adpgk (Adpgk peptide) is an H-2 Kb-restricted colorectal cancer neoantigen peptide. MC38 SLP Adpgk is formulated into PCNP nanocomplexes together with CpG ODN. PCNP vaccines significantly enhance the co-delivery efficiency of neoantigens and adjuvants to lymphoid organs, and activate cytotoxic T cells. PCNP vaccines not only protect mice from MC-38 colorectal tumor invasion, but also exhibit anti-tumor efficacy in established colorectal tumor models and significantly prolong the survival of tumor-bearing mice.
For research use only. We do not sell to patients.
- Purity: 97.52%
- Formula: C128H207N33O38S3
- Molecular Weight:2912.41
-
Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
|
MHC I |
MC38 SLP Adpgk (5 µg/mL; 1.5 h) stimulates naive murine splenocytes to generate peptide-pulsed cells suitable for labeling with CFSE[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
Appearance Solid
-
Molecular Weight 2912.41
-
Formula C128H207N33O38S3
-
Color White to light yellow
-
Synonyms
Adpgk peptide
-
Sequence
Gly-Ile-Pro-Val-His-Leu-Glu-Leu-Ala-Ser-Met-Thr-Asn-Met-Glu-Leu-Met-Ser-Ser-Ile-Val-His-Gln-Gln-Val-Phe
-
Sequence Shortening
GIPVHLELASMTNMELMSSIVHQQVF
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 1 mg/mL (0.34 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Purity & Documentation
-
Data Sheet (275 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)