CD274 - CD274 molecule Gene

Sus scrofa

Also known as PDL1

Gene ID: 574058 | Gene type: protein coding

About CD274

Primary_assembly 1: 216,660,041-216,792,724 reverse strand.Sscrofa11.1:CM000812.5

This gene has 2 transcripts (splice variants), 102 orthologues and 8 paralogues. Broad expression in spleen (RPKM 1.1), ovary (RPKM .8) and 8 other tissues.

CD274 Products(1)

mRNA	Protein	Name
NM_001025221.1	NP_001020392.1	programmed cell death 1 ligand 1 precursor

CD274 Protein Structure

IgV_PDl1

0
100
200
300
361 a.a.

Protein Preferred Names

Protein Names

programmed cell death 1 ligand 1

CD274 antigen

programmed death ligand 1

Related Agents

Clinical Phase

Inhibitory Antibodies (2)

Cat. No.	Product Name	Effect	Purity	Phase
HY-P990014	Danburstotug	Inhibitor	98.76%	Phase 2
HY-P990623	MDX-1105	Inhibitor	≥99.0%	Phase 1

Pre-clinical Phase

Bioactive Molecules (4)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02217	CD274 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS02218	Cd274 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS02219	Cd274 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-14243	CEP-14083	Inhibitor	/	Unkown

Inhibitory Antibodies (10)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P991449	LY3415244	Inhibitor	95.09%	Unkown
HY-P99903	Simridarlimab	Inhibitor	99.81%	Unkown
HY-P990899	Amostomig		97.931%	Unkown
HY-P991024	Solabafusp alfa	Inhibitor	/	Unkown
HY-P99698	Lesabelimab	Inhibitor	97.34%	Unkown
HY-P991151	Opamtistomig	Inhibitor	/	Unkown
HY-P991354	GR-1405	Antagonist	/	Unkown
HY-P991355	PDL-GEX	Antagonist	/	Unkown
HY-P991356	FAZ-053	Antagonist	/	Unkown
HY-P991357	STT-001	Antagonist	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	CD274	NCBI	NCBI:29126
Canis familiaris	CD274	NCBI	NCBI:484186
Macaca fascicularis	CD274	NCBI	NCBI:102145573
Mus musculus	CD274	NCBI	NCBI:60533
Leporidae	CD274	NCBI
Rattus norvegicus	CD274	NCBI	NCBI:499342
Macaca mulatta	CD274	NCBI	NCBI:716043

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