Amostomig
Based on 1 Customer Validation
HY-P990899 is an CD274/CD47-targeting IgG1λ2 type humanized antibody, the recommed isotype control is Human IgG1 lambda2, Isotype Control (HY-P990096).
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté : 97.931%
- CAS No.: 2889449-09-4
- Masse moléculaire:145.225 kDa
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Stockage:Shipping with dry ice
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
Isotype
Human IgG1 lambda2
Recommend Isotype Controls
Species Reactivity
Human
IC50 & Target
CD274 & CD47
Gene ID
Accession
Q9NZQ7 & Q61735-1
Conjugated
Unconjugated
Reconsititution
The product can be reconstituted/diluted with sterile PBS or saline.
Format
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IgG1-lambda
Application
ELISA, FACS, Functional assay
Verified Bioactivity
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Immobilized CD47 Protein, Human (Biotinylated, HEK293, His-Avi, HY-P78095) can bind Amostomig. The EC50 for this effect is 248.4 ng/mL. -
Immobilized PD-L1 Protein, Human (HEK293, HY-P73361) can bind Amostomig. The EC50 for this effect is 157.4 ng/mL. -
Flow cytometric analysis of 1X106 Jurkat cells labeling CD274 with Amostomig (HY-P990899, red). Cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF488-conjugated Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 lambda2 Isotype Control (HY-P990096, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
Chemical Information
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CAS No. 2889449-09-4
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Appearance Liquid
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Masse moléculaire 145.225 kDa
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Color Colorless to off-white
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SMILES
[Amostomig]
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Livraison
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
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Fiche technique (272 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)