Rgr - retinal G protein coupled receptor Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 57811

Summary

The gene is a member of the opsin family of G-protein coupled receptors. The encoded protein is expressed in the retina, and acts as a photoisomerase to catalyze the conversion of all-trans-retinal to 11-cis-retinal. Disruption of a similar gene in human is associated with autosomal recessive (arRP) and autosomal dominant retinitis pigmentosa (adRP). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014]

Rgr Products (3)

mRNA Protein Name
NM_001301692.1 NP_001288621.1 RPE-retinal G protein-coupled receptor isoform 2
NM_001301694.1 NP_001288623.1 RPE-retinal G protein-coupled receptor isoform 2
NM_021340.4 NP_067315.1 RPE-retinal G protein-coupled receptor isoform 1

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in plasma membrane IDA
IDA: Inferred from direct assay
9841934 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

RPE-retinal G protein-coupled receptor

  • RGR opsin

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-181742 ULK1/2-IN-1 / Unkown
HY-RS11893 RGL4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS11901 RGR Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17527 Rgr Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23984 Rgr Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rgr NCBI NCBI:5995