2. Gene
  3. Nckap1 - NCK-associated protein 1 Gene

Nckap1 - NCK-associated protein 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 58823 | Gene type: protein coding

About Nckap1

Summary

Predicted to contribute to small GTPase binding activity. Predicted to be involved in several processes, including Rac protein signal transduction; cortical actin Cytoskeleton organization; and positive regulation of cellular component organization. Predicted to act upstream of or within several processes, including apical protein localization; embryonic morphogenesis; and segmentation. Predicted to be located in lamellipodium and ruffle. Predicted to be part of SCAR complex and filamentous actin. Predicted to be active in postsynapse. Orthologous to human NCKAP1 (NCK associated protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Nckap1 Products(1)

mRNA Protein Name
NM_031618.1 NP_113806.1 nck-associated protein 1
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
8605018 RGD
Cellular Component GO Annotation Evidence Reference Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
25293574 RGD
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
25293574 RGD
is active in postsynaptic density IDA
IDA: Inferred from direct assay
25293574 RGD
is active in postsynaptic density IMP
IMP: Inferred from mutant phenotype
25293574 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

nck-associated protein 1

NAP 1

membrane-associated protein HEM-2

p125Nap1

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09082 NCKAP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS09083 NCKAP1L Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nckap1 NCBI NCBI:10787