Ppp2r3c - protein phosphatase 2, regulatory subunit B'', gamma Gene

Also Known as G4-1; G5pr; 4930511A21Rik; 5730412A08Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 59032

Summary

Predicted to enable metal ion binding activity. Acts upstream of or within several processes, including lymphocyte homeostasis; positive regulation of B cell differentiation; and spleen development. Predicted to be located in Golgi apparatus; cytosol; and nucleoplasm. Predicted to be active in centrosome. Is expressed in embryo. Human ortholog(s) of this gene implicated in spermatogenic failure 36. Orthologous to human PPP2R3C (protein Phosphatase 2 regulatory subunit B''gamma). [provided by Alliance of Genome Resources, Apr 2022]

Ppp2r3c Products (1)

mRNA Protein Name
NM_021529.4 NP_067504.2 serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
18715506 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within B cell homeostasis IMP
IMP: Inferred from mutant phenotype
16129705 MGI
acts upstream of or within T cell homeostasis IMP
IMP: Inferred from mutant phenotype
16129705 MGI
acts upstream of or within activation of protein kinase activity IMP
IMP: Inferred from mutant phenotype
16129705 MGI
acts upstream of or within positive regulation of B cell differentiation IMP
IMP: Inferred from mutant phenotype
16129705 MGI
acts upstream of or within regulation of B cell activation IMP
IMP: Inferred from mutant phenotype
16129705 MGI
acts upstream of or within regulation of antimicrobial humoral response IMP
IMP: Inferred from mutant phenotype
16129705 MGI
acts upstream of or within regulation of mitochondrial depolarization IMP
IMP: Inferred from mutant phenotype
16129705 MGI
acts upstream of or within spleen development IMP
IMP: Inferred from mutant phenotype
16129705 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma

  • phosphatase subunit gene g4-1

  • protein phosphatase subunit G5PR

Orthologs Information

Species Symbol Source ID
Homo sapiens Ppp2r3c NCBI NCBI:55012